abstract：:We present the case of a 30-year-old woman who suddenly developed intense occipital headaches. Computed tomography and magnetic resonance imaging demonstrated a cyst located ventrally to the brain stem at the pontomedullary junction. The lesion was resected. Histologically, it was lined by a pseudostratified, ciliated...

journal_title：Archives of pathology & laboratory medicine

authors： Albrecht S,Robertson DP,Goodman JC,Harper RL

更新日期：1992-02-01 00:00:00

abstract：:Amplification of the neu oncogene and overexpression of its product was found to be a potential marker for aggressive biological behavior in breast cancer. However, the expression of the neu oncoprotein in normal breast ducts and myoepithelial cells has also been demonstrated. Hence, we examined normal salivary gland ...

journal_title：Archives of pathology & laboratory medicine

authors： Kahn HJ,Hanna W,Auger M,Andrulis I

更新日期：1992-01-01 00:00:00

abstract：:In a series of 1137 diagnostic breast biopsy specimens in a 2-year period, nearly half (n = 534) underwent specimen mammography. Calcifications were found in 48% of the specimen mammograms. In a quarter of the cases, calcification was a marker either for carcinoma or a significant precursor lesion. Moreover, in the ma...

journal_title：Archives of pathology & laboratory medicine

authors： Symonds DA,Copeland BE,Drane A,Kaplan GN,Graham RR

更新日期：1992-01-01 00:00:00

abstract：:A 3680-g term male neonate developed bilateral bronchopneumonia at 9 days of age. The labor, delivery, and immediate postnatal period had been unremarkable. Despite standard antibiotic therapy, the patient progressed to respiratory failure and died 4 days later. Adenovirus particles were found in oropharyngeal secreti...

journal_title：Archives of pathology & laboratory medicine

authors： Pinto A,Beck R,Jadavji T

更新日期：1992-01-01 00:00:00

abstract：:Transmission and scanning electron microscopic examinations were performed to evaluate the fine-structural differences in sinusoids of hepatocellular carcinoma, adenomatous hyperplasia of the liver, and fetal livers. In cancerous sinusoids, thickened endothelial cells with loss of sieve plates were conspicuous feature...

journal_title：Archives of pathology & laboratory medicine

authors： Haratake J,Hisaoka M,Yamamoto O,Horie A

更新日期：1992-01-01 00:00:00

abstract：:The significance of an elevated free thyroxine index (FTI) as an indicator of hyperthyroidism was studied while screening 651 elderly nursing home residents. Eleven subjects had FTI elevations. Most of these patients were chronically ill and/or malnourished. Clinical assessment, repeated FTI determinations, and subseq...

journal_title：Archives of pathology & laboratory medicine

authors： Drinka PJ,Nolten WE,Voeks S,Langer E,Carlson IH

更新日期：1991-12-01 00:00:00

abstract：:In a series of 342 bone marrow examinations from 314 patients with human immunodeficiency virus infection, 70 examinations (20%) detected opportunistic mycobacterial or fungal infections. One hundred eleven of the 314 patients had such infections, and, hence, 63% (70/111) were detected by bone marrow examination. Spec...

journal_title：Archives of pathology & laboratory medicine

authors： Nichols L,Florentine B,Lewis W,Sattler F,Rarick MU,Brynes RK

更新日期：1991-11-01 00:00:00

abstract：:Benign clear cell ("sugar") tumor is a rare and most unusual pulmonary neoplasm. Although several reports in the literature have focused on the ultrastructural features of benign clear cell tumor, only a few cases have been formally studied by immunochemistry. Using a broad panel of polyclonal and monoclonal antibodie...

journal_title：Archives of pathology & laboratory medicine

authors： Gal AA,Koss MN,Hochholzer L,Chejfec G

更新日期：1991-10-01 00:00:00

abstract：:Coccidioidomycosis has been reported in almost every tissue of the human body. The gastrointestinal tract and breast have been uniquely spared from this fungal infection. Despite the exceedingly large number of screening mammographies that are performed every year, to our knowledge subcutaneous breast tissue involveme...

journal_title：Archives of pathology & laboratory medicine

authors： Bocian JJ,Fahmy RN,Michas CA

更新日期：1991-10-01 00:00:00

abstract：:We present an autopsy case of a 29-week-old male fetus with a very unusual set of congenital granular cell tumors, including gingival epulis and granular cell lesions of the kidneys, lung, heart, esophagus, small and large intestine, thyroid, adrenals, spleen, urinary bladder, testis, pituitary, and leptomeninges. The...

journal_title：Archives of pathology & laboratory medicine

authors： Park SH,Kim TJ,Chi JG

更新日期：1991-09-01 00:00:00

abstract：:During a surgical procedure, black vertebrae were observed in a 42-year-old white woman. An undecalcified iliac crest bone biopsy specimen revealed intense fluorescence compatible with tetracycline labeling and osteoporosis. A urinary screening test was negative for amino acids. The patient had been treated with minoc...

journal_title：Archives of pathology & laboratory medicine

authors： Rumbak MJ,Pitcock JA,Palmieri GM,Robertson JT

更新日期：1991-09-01 00:00:00

abstract：:Patients with xeroderma pigmentosum (XP) experience cutaneous and ocular abnormalities, including neoplasia of epithelial and melanocytic cellular origin. Black patients with XP display more severe ocular abnormalities and neoplasia. We report the clinicopathologic findings in two black young children with XP who pres...

journal_title：Archives of pathology & laboratory medicine

authors： Pe'er J,Levinger S,Chirambo M,Ron N,Okon E

更新日期：1991-09-01 00:00:00

abstract：:The monoclonal antibody HMB-45 is a highly specific and sensitive marker of malignant melanoma. Rarely, however, aberrant reactivity to nonmelanocytic tumors has been observed. We report an immunoblastic lymphoma of B-cell phenotype that reacted with HMB-45 in a 70-year-old white woman. To our knowledge, this is the f...

journal_title：Archives of pathology & laboratory medicine

authors： Friedman HD,Tatum AH

更新日期：1991-08-01 00:00:00

abstract：:An adenoma of type 2 pneumocytes in the periphery of the left lung was an incidental finding at the autopsy of a 28-year-old woman. Light microscopy revealed a predominantly papillary growth with oncocytic features. Ultrastructurally, multilaminated bodies and many mitochondria were found in the tumor cells and tubula...

journal_title：Archives of pathology & laboratory medicine

authors： Fine G,Chang CH

更新日期：1991-08-01 00:00:00

abstract：:Histopathology is based on the interpretation of features of the microscopic image. In recent years, there has evolved interest in assessing quantifiable data from these images, with the intent of providing more precise diagnostic and prognostic information. Proliferation characteristics of tumors are among the most i...

journal_title：Archives of pathology & laboratory medicine

authors： Woosley JT

更新日期：1991-06-01 00:00:00

abstract：:We encountered a rare case of pulmonary phaeohyphomycosis due to Xylohypha bantiana documented by culture. This dematiaceous (darkly pigmented) fungus is primarily neurotropic. It usually produces phaeohyphomycosis of the central nervous system but may also involve the skin and subcutaneous tissues. The patient, a 49-...

journal_title：Archives of pathology & laboratory medicine

authors： Borges MC Jr,Warren S,White W,Pellettiere EV

更新日期：1991-06-01 00:00:00

abstract：:The application of immunohistochemical markers against epithelial antigens has proved useful for studying tumor differentiation and in aiding tumor diagnosis. However, the reactivity of various epithelial markers with poorly differentiated carcinomas (the situation in which they are most often used) has not been well ...

journal_title：Archives of pathology & laboratory medicine

authors： Kamel OW,Rouse RV,Warnke RA

更新日期：1991-06-01 00:00:00

abstract：:The ability of the College of American Pathologists Microbiology Surveys subscriber laboratories to perform antimicrobial susceptibility testing accurately has improved slightly since 1984. Currently (1989 surveys), the accuracies for disk diffusion and minimum inhibitory concentration antimicrobial susceptibility tes...

journal_title：Archives of pathology & laboratory medicine

authors： Jones RN,Edson DC

更新日期：1991-05-01 00:00:00

abstract：:We analyzed the autopsy records of 261 patients with breast carcinoma, who died at The Institute of Oncology, Ljubljana, Yugoslavia, for the presence of metastases to the central nervous system, particularly for the presence of leptomeningeal carcinomatosis. Metastases to the central nervous system were found in 41 (1...

journal_title：Archives of pathology & laboratory medicine

authors： Lamovec J,Zidar A

更新日期：1991-05-01 00:00:00

abstract：:Rapid tissue diagnosis during acute events associated with renal transplantation is often necessary to permit immediate decisions regarding initiation or modification of therapy. To achieve this, we performed frozen section analyses with cryoprotected alcoholic Bouin's-fixed tissue, which permits evaluation within 2.5...

journal_title：Archives of pathology & laboratory medicine

authors： Cohen AH,Gonzalez S,Nast CC,Wilkinson A,Danovitch GM

更新日期：1991-04-01 00:00:00

abstract：:We report a case of primary rhabdomyosarcoma of the ileum occurring in a 45-year-old man. The rhabdomyoblastic nature was immunohistochemically confirmed by positivity with anti-myoglobin and anti-striated actin antisera. We discuss the differential diagnosis with similar tumors. To our knowledge, ileal rhabdomyosarco...

journal_title：Archives of pathology & laboratory medicine

authors： Damiani S,Nappi O,Eusebi V

更新日期：1991-03-01 00:00:00

abstract：:Allogeneic marrow transplants from genotypically HLA-identical siblings have become lifesaving therapy for patients with various congenital and acquired diseases of the immune and hematopoietic systems. Unfortunately, less than 30% of patients in the United States have an HLA-identical sibling; therefore, many are den...

journal_title：Archives of pathology & laboratory medicine

authors： Anasetti C

更新日期：1991-03-01 00:00:00

abstract：:We recently encountered a unique case of follicular variant of papillary carcinoma arising in struma ovarii that contained numerous intrafollicular crystalloids. There was no evidence of capsular or vascular invasion or metastases, though the DNA content of the papillary carcinoma was aneuploid. In contrast, diploid D...

journal_title：Archives of pathology & laboratory medicine

authors： Ro JY,Sahin AA,el-Naggar AK,Ordonez NG,Mackay B,Llamas LL,Ayala AG

更新日期：1991-02-01 00:00:00

abstract：:This project was designed to evaluate different criteria used in the interpretation of the human immunodeficiency virus type 1 (HIV-1) Western blot assay on a group of serum samples blinded to the examiner that were collected from individuals attending three different public health departments in central North Carolin...

journal_title：Archives of pathology & laboratory medicine

authors： O'Gorman MR,Weber D,Landis SE,Schoenbach VJ,Mittal M,Folds JD

更新日期：1991-01-01 00:00:00

abstract：:A case of systemic idiopathic fibrosis was analyzed by Southern blotting with probes to the immunoglobulin heavy chain and T-cell receptor genes. A 45-year-old man presented with bilateral neck swelling. He later developed lower back pain, and findings on a computed tomographic scan were consistent with idiopathic ret...

journal_title：Archives of pathology & laboratory medicine

authors： Dent GA,Baird DB,Ross DW

更新日期：1991-01-01 00:00:00

abstract：:While the level of marrow reticulin may be a factor that is used when the presence of a hematologic disorder is being considered, to our knowledge no study has graded the amount of reticulin present in normal iliac bone marrow. Grading reticulin stains of bone biopsy specimens from 100 hematologically normal patients ...

journal_title：Archives of pathology & laboratory medicine

authors： Beckman EN,Brown AW Jr

更新日期：1990-12-01 00:00:00

abstract：:Concerns regarding significant levels of inappropriate medical services--as high as 20% or more--continue to influence discussions regarding medical care quality, utilization, and costs. The basis of these concerns are findings from a series of studies of the appropriateness of use of several medical and surgical serv...

journal_title：Archives of pathology & laboratory medicine

authors： Kelly JT,Kellie SE

更新日期：1990-11-01 00:00:00

abstract：:The costs of producing quality medical care and the proper allocation of resources to assure quality are major contemporary concerns. Minimalists attempt to improve quality and lower costs through the application of the theory, "less is more." Bureaucracies make the same attempt through the denial of payments for "unn...

journal_title：Archives of pathology & laboratory medicine

authors： Lambird PA

更新日期：1990-11-01 00:00:00

abstract：:Fifty-seven cervical biopsy specimens or endocervical curettings showing condyloma, changes suggestive of condyloma, or no changes of condyloma were analyzed for presence of nuclear atypia (nuclear enlargement and irregularity in superficial epithelium), presence of multinucleated cells, and presence of perinuclear cy...

journal_title：Archives of pathology & laboratory medicine

authors： Mittal KR,Chan W,Demopoulos RI

更新日期：1990-10-01 00:00:00

abstract：:Patients with alloantibodies may request directed blood donations from their relatives despite the lack of any scientific data suggesting that blood from these donors is safer. We have derived formulas that are applicable to any ethnic group for calculating the probability that a given class of relatives will have com...

journal_title：Archives of pathology & laboratory medicine

authors： Kanter MH,Hodge SE

更新日期：1990-10-01 00:00:00

abstract：:Pulmonary blastomas are rare primary tumors that consist of tubular or glandular structures embedded in an undifferentiated mesenchymal stroma. Focal cartilage, bone, and skeletal muscle as well as squamous differentiation have been described in these tumors. We report a unique case of a pulmonary blastoma showing a m...

journal_title：Archives of pathology & laboratory medicine

authors： Cohen RE,Weaver MG,Montenegro HD,Abdul-Karim FW

更新日期：1990-10-01 00:00:00

abstract：:The frequency of light chain deposition nephropathy relative to renal amyloidosis and Bence Jones cast nephropathy was determined in a necropsy study of 57 patients with myeloma. The diagnosis of light chain deposition nephropathy was established by immunofluorescence microscopic examination of kidney tissue demonstra...

journal_title：Archives of pathology & laboratory medicine

authors： Iványi B

更新日期：1990-09-01 00:00:00

abstract：:The increasing interest in geriatric medicine demands an understanding of aging in human tissues. The changes in the human heart are an important aspect of this understanding because cardiovascular diseases are a leading medical problem in the elderly. The published data about age-related changes in the human myocardi...

journal_title：Archives of pathology & laboratory medicine

authors： Klima M,Burns TR,Chopra A

更新日期：1990-09-01 00:00:00

abstract：:Sensitivity, specificity, and predictive values are commonly used to report the performance characteristics of a diagnostic test. With tests that by their nature have more than two classes of results, calculation of sensitivity and specificity demands the combination of categories into two classes, leading to a loss o...

journal_title：Archives of pathology & laboratory medicine

authors： Giard RW,Hermans J

更新日期：1990-08-01 00:00:00

abstract：:Nonneoplastic vascular lesions in lymph nodes have been infrequently reported. These lesions are believed to be rare and display histologic features ranging from minimal changes associated with vasodilation to vascular proliferative lesions resembling Kaposi's sarcoma. The spectrum of histologic features observed in t...

journal_title：Archives of pathology & laboratory medicine

authors： Ostrowski ML,Siddiqui T,Barnes RE,Howton MJ

更新日期：1990-07-01 00:00:00

abstract：:The risks of homologous blood transfusion have motivated some blood centers and private industry to consider providing long-term storage of frozen, autologous red blood cells as a service. The usefulness of this practice is unknown. We performed a retrospective analysis of frozen autologous red blood cell use in two h...

journal_title：Archives of pathology & laboratory medicine

authors： DePalma L,Palmer R,Leitman SF,Dolan WD,Klein HG

更新日期：1990-05-01 00:00:00

abstract：:To our knowledge this is the first reported case of concurrent Merkel cell (trabecular carcinoma) tumor and peripheral pulmonary carcinoid tumor. Both tumors are considered to neuroendocrine in nature. The significance of concurrent neuroendocrine tumors is described with respect to multiple endocrine neoplasia syndro...

journal_title：Archives of pathology & laboratory medicine

authors： Nelson EL,Houghton DC

更新日期：1990-04-01 00:00:00

abstract：:A 48-year-old Japanese woman died of multiple myeloma (lambda light-chain type) with chronic renal failure. Histological examination revealed deposition of a homogeneous substance and crystals in the kidneys and thyroid gland. The homogeneous substance was stained with Congo red after permanganate treatment but did no...

journal_title：Archives of pathology & laboratory medicine

authors： Hirota S,Miyamoto M,Kasugai T,Kitamura Y,Morimura Y

更新日期：1990-04-01 00:00:00

abstract：:The existence of facultative stem cells in the liver has been advocated based on observations from models of carcinogenesis in rat liver. Observations of human liver material from cases of fulminant hepatitis have shown the presence of ductular hepatocytes expressing markers of both hepatocytes and bile duct cells. We...

journal_title：Archives of pathology & laboratory medicine

authors： Vandersteenhoven AM,Burchette J,Michalopoulos G

更新日期：1990-04-01 00:00:00

abstract：:Indirect immunofluorescence antibody testing is a mainstay of retrovirus serodiagnosis in the public health community, affording quick, inexpensive, and clear results with significant advantages over Western blot testing. Limitations regarding training of personnel and availability of reagents will probably continue a...

journal_title：Archives of pathology & laboratory medicine

authors： Ascher MS,Wilber JC

更新日期：1990-03-01 00:00:00